Pesquisa sobre:
VASCULAR ENDOTHELIAL GROWTH FACTOR A
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DeCS
Descritor
Inglês
:
Vascular Endothelial Growth Factor A
Descritor
Espanhol
:
Factor A de Crecimiento Endotelial Vascular
Descritor
Português
:
Fator A de Crescimento do Endotélio Vascular
Sinônimos
Inglês
:
Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor-A
Categoria:
D12.644.276.100.800.200
D12.776.467.100.800.200
D23.529.100.800.200
Definição
Inglês
:
The original member of the
family
of endothelial cell
growth
factors referred to as
VASCULAR ENDOTHELIAL GROWTH FACTORS
. Vascular endothelial
growth
factor-A was originally isolated from tumor
cells
and referred to as "tumor angiogenesis factor" and "vascular
permeability
factor". Although expressed at high levels in certain tumor-derived
cells
it is produced by a wide variety of cell types. In addition to stimulating vascular
growth
and vascular
permeability
it may play a
role
in stimulating
VASODILATION
via NITRIC OXIDE-dependent pathways.
Alternative splicing
of the mRNA for
vascular endothelial growth factor A
results in several isoforms of the protein being produced.
Nota Histórica
Inglês
:
2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
38244
Identificador Único:
D042461
Ocorrência na BVS
:
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